ea0063p623 | Diabetes, Obesity and Metabolism 2 | ECE2019
Emna Jelloul
, Fontaine Benedicte
, Vanderbecken Stephane
, Meliani Pascal
, Kembellec Candice
, Flaus-Furmaniuk Ania
, Debussche Xavier
Insulin autoimmune syndrome (IAS; Hirata syndrome) is a rare cause of hypoglycemia. It seems to be related to specific HLA class II alleles. Rarely, monoclonal antibody acts as an insulin-binding autoantibody: until now 10 cases have been described in association with a myeloproliferative disorder. In June 2015, a 60-year-old patient presented in a local hospital in Mayotte with confusion, sweating and severe hypoglycemia (blood glucose as low as 20 mg/dl). He was suffering of...